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Prebiotic 3-In-1 MultiMist

Mist replenishes with prebiotics, primes and sets makeup.

What it does:

A peptide-rich, hydrating mist that replenishes with prebiotics to balance skin’s microbiome for healthier-looking skin. This 3-in-1 formula features hydrating sugars to moisturize and refresh skin, while a yeast peptide helps lock in hydration. A multi-tasking biopolymer complex primes and sets makeup.

What else you need to know:

Which skin type is it good for?

  • Normal
  • Oily
  • Combination
  • Dry
  • Sensitive

Formulated without:

  • Parabens
  • Sulfates
  • Phthalates
  • Gluten
  • Dyes
  • GMOs
  • Oil
  • Triclosan
  • Alcohol
  • Nuts
  • Animal-derived ingredients
  • Nanoparticles

Prebiotic 3-In-1 MultiMist is rated 4.5 out of 5 by 32.
Rated 5 out of 5 by from A must have. Really happy with this, not only sets my make up it gives a lovely dewy finish! Make up lasts all day.
Date published: 2019-09-19
Rated 5 out of 5 by from Amazing multi mist I got this product over 6 weeks ago and have been using it on days that have been wearing makeup. Murad multi mist can be used as a prep before putting makeup on and the can be used as a setting spray to set makeup, and also to refresh your makeup too. I would usually use the urban decay all nighter spray, but I've feel this product is better in the sense that you can use it as all 3 and not just a setting spray, and it gives you a more natural mattifying finish which is perfect for combination skin, and oily skin and if you prefer a matte finish. My makeup has stayed emaculate all day when I have used this product, even on days when its very hot, even on days were i have had a hour work at the gym. This product deserves five stars!!
Date published: 2019-05-16
Rated 5 out of 5 by from I have been using this multi-mist for a couple of weeks now. After using it for a couple days I noticed my make up looking more refreshed throughout the day. I use it as a primer before I put my make up on and after make up has been applied to set it. I only need to use it once more through the day. It has a nice subtle smell as well and comes in a thin bottle so perfect to keep in your bag! All in all very pleased with this product!
Date published: 2019-03-26
Rated 4 out of 5 by from Multi-Mist I have been trying this product for a couple of weeks now and I am really impressed of how easy it is to use and is absorbed into the skin really quickly. I use this when I get out of the shower and before I go to bed and it has made my skin feel really refreshed.
Date published: 2019-03-20
Rated 3 out of 5 by from Product is okay I got this product around 3 weeks ago and have used it twice a day since getting it. It feels like I’ve sprayed my face with water when I first use it, but it dries very quickly, but does not leave my face feeling dry like it does after washing. I have noticed my skin to feel more hydrated since using this product.
Date published: 2019-03-18
Rated 5 out of 5 by from The best skincare product I've used in ages! I have been using Murad's Prebiotic 3-In-1 MultiMist spray for just over 2 weeks and the difference to my skin has been incredible and so noticeable! It recommends using it the product twice a day, so I've been using it in the mornings after applying make up as a make-up setter, and then in the evenings after moisturising, just before sleeping. My skin feels much fresher and more even in complexion. I was suffering one morning from the night before (lack of sleep and a cocktail making class...) but my skin felt so fresh and radiant - much better than the usual dryness I'd wake up feeling in the morning! It's also really effective as a make up setter. Would definitely recommend and it seems like it'll last sometime too as two sprays go pretty far!
Date published: 2019-03-18
Rated 4 out of 5 by from Great to use after make up I have been using this product a bit more than two weeks. I have used it on skin without make up and with make up. It maintain the make up on and refresh the skin making sure it is hydratated. Very easy to use.
Date published: 2019-03-18
Rated 5 out of 5 by from Woke up my tired skin I’ve been using this for over ten days now. My skin is more bright and alive than ever before. I use it last thing at night after my skincare routine and have noticed a huge difference in my skin. It’s so much more alive looking.
Date published: 2019-03-16
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Solution for:

  • Dehydration
  • Dullness
  • Fine lines and wrinkles
  • Uneven skin texture
  • Priming and setting makeup

This product is:

  • Cruelty-free
  • Safe for sensitive skin

Dr.'s inspiration:

“The obsession with anti-bacterial products and harsh cleansers is destroying bad bacteria—but stripping away good bacteria, too. When combined with continued allergen and toxin assaults, essential bacteria are thrown out of whack and skin issues occur. Prebiotic 4-in-1 MultiCleanser and Prebiotic 3-in-1 MultiMist nourish skin with prebiotics to rebalance the skin's microbiome, which is the collection of bacteria living on skin. This keeps skin well-hydrated, balanced and healthier-looking overall." —Dr. Howard Murad, M.D., FAAD

How To Use

To use: AM and PM

  1. Hold bottle 8-10 inches away from face, close eyes and mist evenly onto skin.
  2. Can be applied under makeup to prime or after makeup to set.
  3. Use to refresh throughout the day.
  4. Warning: Avoid getting into eyes.

Use with:


Ingredient spotlight:

Prebiotic hydrating sugars

Promote enrichment of good bacteria. Reinforce and help boost skin's natural hydration reserves for a smooth, healthy barrier.

Yeast peptide

Help lock in skin’s natural moisture levels to promote healthy, hydrated skin, which, in turn, supports an ideal environment for a healthy microbiome.

Bipolymer complex

Forms a natural, breathable, surface-smoothing second skin that helps prime and set makeup, and ensure longer makeup wear.


Water/Aqua/Eau, Glycerin, Propanediol, Niacinamide, Hydrolyzed Yeast Protein, Caesalpinia Spinosa Fruit Extract, Kappaphycus Alvarezii Extract, Saccharide Isomerate, Xylitylglucoside, Anhydroxylitol, Xylitol, Zinc Gluconate, Caffeine, Hydroxyethyl Urea, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Butylene Glycol, Pentylene Glycol, Caprylhydroxamic Acid, 1,2 Hexanediol, Divinyldimethicone/Dimethicone Copolymer, Acrylates/Polytrimethylsiloxymethacrylate Copolymer, C12-13 Pareth-3, C12-13 Pareth-23, Laureth-1 Phosphate, Polysorbate 20, Fragrance (Parfum)